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Did you know that the separation step is where most nutraceutical manufacturers win or lose their bioactive value?

Written by Sven Cammerer | Jun 29, 2026 11:55:44 AM

The nutraceutical industry sits at the intersection of science, trust, and human wellbeing. Whether your products support cognitive health, immune system, or healthy ageing, what you manufacture matters to real people who depend on it.  

The challenge

Ranging from processing marine oils, plant-based extracts, fermentation broths, or synthetic vitamins, your feedstocks are rich in high-value bioactives, yet conventional separation processes recover only a fraction of what they actually contain. At every stage, your process is costing you more than you realize:

  • High product losses and thermal degradation of sensitive actives
  • Residual solvents, contaminants, and batch-to-batch inconsistency
  • Excessive energy consumption
  • Regulatory compliance pressure including FDA, GMP and ISO, with no margin for error

The opportunity

Your process streams hold more value than you are currently recovering. From omega-3 concentration to vitamin E purification, carotenoid recovery to CBD solvent removal, the right separation technology optimizes the economics and efficiency of your entire operation. Recovering and concentrating your bioactives with precision will lead to higher-grade products, better margins, and a cleaner label.  

The solution

Sulzer combines four complementary technologies, deployable standalone or integrated skid solutions, to address the full range of separation challenges across all feedstock types to:

  • Achieve pharmaceutical grade purity for your most demanding bioactives
    DistilCare™ continuous vacuum distillation operates below 1 mbar, delivering single-pass concentration with minimal thermal compromise.
  • Protect every heat-sensitive active from extract to final concentrate
    EvapCare™ evaporator maintains product integrity thanks to ultra-short residence time, while enabling efficient solvent removal
  • Reach >99% purity in a single cycle for every batch
    Excelot™ flexible batch purification eliminates multi-column complexity and delivers the consistency regulators and practitioners demand.
  • Recover more at room temperature, without sacrificing bioactivity
    OptimEXT™ selective extraction operates without heat, achieving >99% recovery at up to 50% lower energy demand

The impact

When separation is optimized, performance improvements are measurable across bioactive manufacturing processes. Sulzer’s technologies consistently deliver outcomes that hold up under the scrutiny of regulators, practitioners and consumers alike, proven in the field:

  • > 99.9% product purity
  • +82% productivity increase
  • Up to 70% energy savings
  • Improved process efficiency and compliance with regulatory standards

All solutions are factory-validated, plug-and-play, and compliance-ready for EU/FDA/GMP standards. Pilot testing with your own material goes beyond performance validation. It delivers process guarantee that stands behind every label claim you make.

Let’s talk about what your process could become and the products only you could make